I have some major discrepancies here, it seems to me that your having an overactive imagination, cuz some of this stuff is coming out of Left field, no pun intended:>)

the already has a SE, FL, and a Slot player lined up

You seem to be under the impression that Ginn played in the wildcat, he didn’t, NO WRs in our wildcat last year, 2 TEs and 3RBs, Chad split-out, Ricky in the slot and usually Cobbs in the short slot, no FL.

You want to run power off T? Fine. With Wilford, London, or Turner in at Slot, you probably don’t lose too much over a TE as a blocker;; And you also put one of those big guys out at SE instead of the QB, which now takes up another DB, and probably requires Safety help

The best blocking WR in the league is no match for the worst blocking TE in the league, WRs block DBs, TEs and RBs block DEs and LBs. I’m talking about squaring up on the line blocking here, not crack backing, Hines Ward is the best crack back blocker in the league, but he would be the first to tell you, he can’t square up on a LB.
Wilford, London, or Turner will never command double teams, they are just not fast enough.

And you have to be able to play-action off of it to keep the Defense from gaining that extra step rushing to the ball carrier.;;You pass off a PA, boot, fleaflicker, etc.

You can’t use PA out of the shotgun, hence you can’t bootleg, cuz the bootleg is an extension of the PA. PA is when the QB is under center and fakes the hand off with his back to the defense so he can “hide” the ball, since there is no running back behind you, you can’t use PA, and bootleg gets its name from that “hiding” of the ball, just like the bootleggers were “hiding” whiskey from the law.
You can certainly fake a hand off, or run out to the flat to throw the ball, but since you can’t “hide” the ball, you wont fool the defense, and PA and bootleg is all about fooling the D.

So, except for the Flanker (Ginn), you still have the ball carrier and 9 blockers on a Power run Off T or sweep. But instead of the D bringing in an extra LB or SS for run support, or bringing 8 or 9 guys in the box like last year, they are forced to protect against the pass. You GAIN a BIG advantage in the run game!

You can certainly gouge the D on a run play out of the spread, but first you have to establish a dangerous passing game, its the opposite of the wildcat, we were very successful when we threw it out of the wildcat, cuz of how dangerous we were running out of that formation, in the spread the pass sets up the run, in the wildcat the run sets up the pass, in the spread the run is a surprise, in the wildcat the pass is a surprise, and thats why it works in both formations.
The reason they can’t put 8 or 9 in the box is because you don’t have as many in the box, its a two way street, so now you have less blockers in the box.

And what do you lose with White as a runner?

Speed, power and maybe a QB. The R&R boys are both faster, and everyone on the team is stronger, including kickers! And if we are serious about White as a QB, you can’t have him lower his shoulder and slam into the line, the risk of injury is too great, suppose White hits the hole and KABLAM he gets tattooed by a safety or a LB, is that how you want to use a QB?

He is not a small guy by RB standards in general, and certainly not by scat back standards. Put 5 lbs or so on him and he is Cobbs size; 10 lbs and he is Darren McFadden’s size. He’s not a grind it out, "30 carries a game" back like Ronnie, but he can certainly attack the middle of the line. Especially in the WC, because the point of the direct snap out of the shotgun is to give the runner the ability to see where the hole develops and hit it.

But he is small for a RB, 220LBs is the avg. for NFL RBs, but regardless he is not a RB, RBs are conditioned over time to be able to take the pounding that they take, its no secret that RBs take the most abuse in the NFL, which is why they have the shortest careers of any position.
When White was in college and a Safety or LB was bearing down on him, he did what any QB would do, he slid, do you want him to do that in the back field when there is no hole?

The wildcat was designed to out man the D on one side of the field on running plays, when you spread the O out you lose that, cuz remember your trying to take a power running formation, and turn it into a passing formation, which brings me back to my initial point, if you want to run the spread, run the spread, if you want to run the wildcat, run the wildcat, trying to combine them, IMO, weakens both.
:>)